2019年1月31日，欧盟食品安全局发布关于来自非转基因谷氨酸棒状杆菌的L-缬氨酸用于饲料和饮用水的安全性和有效性的评估结果。据了解，非转基因谷氨酸棒杆菌菌株KCCM 11201P发酵生产的L-缬氨酸拟用于所有动物种类和类别的饲料和饮用水中。经过评估，欧盟食品安全局认为看，这种L-缬氨酸的使用对目标物种是安全的，也是所有物种缬氨酸的有效来源。部分原文报道如下：The product subject of this assessment is l‐valine produced by fermentation using a non‐genetically modified strain of Corynebacterium glutamicum （KCCM 11201P）。 It is intended to be used in feed and water for drinking for all animal species and categories. Species identity of the production organism was confirmed and the strain was sensitive to antibiotics at concentrations below thresholds specified by EFSA, thus C. glutamicum KCCM 11201P may be considered safe by the qualified presumption of safety （QPS） approach. No viable cells of C. glutamicum were detected in the final product. The amount of identified material exceeded ■■■■■% on 'as is' basis, and no impurities of concern were detected. The use of l‐valine produced by C. glutamicum KCCM 11201P is safe for target species when supplemented to diets in appropriate amounts, for the consumer and the environment. The product l‐valine produced by C. glutamicum （KCCM 11201P） is considered not to be an irritant or a dermal sensitiser, and does not cause acute inhalation toxicity. The additive is an effective source of valine for all species. For the supplemental l‐valine to be as efficacious in ruminants as in non‐ruminant species, it requires protection against microbial degradation in the rumen.
